Intersecting epidemics Tuberculosis (TB) remains a considerable global public health concern, mainly affecting poor and vulnerable populations. Every year, more than 9 million people fall ill with this infectious disease, and close to 2 million die from it. Diabetes, a chronic metabolic disease that is i...
Research over the past decade has resulted in the development of two commercial interferongamma release assays (IGRAs), based on the principle that the T-cells of individuals who have acquired TB infection respond to re-stimulation with Mycobacterium tuberculosis-specific antigens by secreting interferon...
Earlier and improved tuberculosis (TB) case detection - including smear-negative disease, often associated with HIV co-infection - as well as expanded capacity to diagnose multidrug-resistant tuberculosis (MDR-TB) are global priorities for TB control. Conventional laboratory methods are slow and cumberso...
